Endometrial Carcinoma: Aetiology, Pathogenesis and Diagnosis

Endometrial Carcinoma: Aetiology, Pathogenesis and Diagnosis presents a comprehensive and contemporary examination of one of the most common gynecological malignancies. Structured to bridge foundational pathology with clinical application, the book offers an in-depth understanding of the progression from normal endometrial physiology to neoplastic transformation.

This work systematically explores the biological, molecular, and diagnostic dimensions of endometrial carcinoma, combining scientific rigor with strong clinical relevance.

The book covers:

• The Pathogenetic Spectrum: Detailed insights into molecular pathways of tumorigenesis, along with the influence of metabolic and endocrine factors in disease development.
• Advanced Diagnostic Approaches: Clear guidance on histopathological grading and staging, including the expanding role of immunohistochemistry with focused discussion on PR, AR, and p53 expression.
• Clinical-Radiological Integration: Examination of CT-guided biopsies and the correlation of radiological findings with histopathological evidence.
• Aetiological Perspectives: Comprehensive evaluation of risk factors, precursor lesions, and the evolving clinical landscape of endometrial cancer.

Richly supported by high-resolution photomicrographs, this volume serves as a valuable reference for postgraduate students, practicing pathologists, gynecologists, and oncologists seeking to enhance diagnostic precision and deepen their understanding of disease mechanisms.